Uracil Debases Pathogenic but Not Commensal Bacteria
نویسندگان
چکیده
منابع مشابه
Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis.
The pathogenesis of Crohn's disease has been associated with a dysregulated response of the mucosal immune system against intraluminal Ags of bacterial origin. In this study, we have investigated the effects of germfree (GF) conditions in the SAMP1/YitFc murine model of Crohn's disease-like ileitis. We show that the bacterial flora is not essential for ileitis induction, because GF SAMP1/YitFc ...
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ژورنال
عنوان ژورنال: Cell Host & Microbe
سال: 2013
ISSN: 1931-3128
DOI: 10.1016/j.chom.2013.04.013